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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-181a
ncRNA name hsa-miR-181a
ncRNA Category miRNA
Disease name posterior capsule opacification (PCO)
Species Homo sapiens
Tissues/Cell_line lens epithelial cells; human lens epithelial cell line SRA01/04
Methods transfection, qRT-PCR, MTT assay, BrdU incorporation assay, transwell assay, Western blot, luciferase reporter assay
Expression pattern down-regulated
Functional description miR-181a directly targets c-Met, Slug, and COX-2. miR-181a can inhibit the proliferation, migration, and EMT of LECs
PubMed ID 25626972
Year 2015
Title miRNA-181a inhibits the proliferation, migration, and epithelial-mesenchymal transition of lens epithelial cells.
Drug-related ncRNA NO

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