ncRNA name | hsa-miR-181a |
ncRNA Category | miRNA |
Disease name | posterior capsule opacification (PCO) |
Species | Homo sapiens |
Tissues/Cell_line | lens epithelial cells; human lens epithelial cell line SRA01/04 |
Methods | transfection, qRT-PCR, MTT assay, BrdU incorporation assay, transwell assay, Western blot, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | miR-181a directly targets c-Met, Slug, and COX-2. miR-181a can inhibit the proliferation, migration, and EMT of LECs |
PubMed ID | 25626972 |
Year | 2015 |
Title | miRNA-181a inhibits the proliferation, migration, and epithelial-mesenchymal transition of lens epithelial cells. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.